Publications

Recent papers:

Ploeger JM, Manivel JC, Boatner LN, Mashek DGCaloric restriction prevents carcinogen-initiated liver tumorigenesis in mice. Cancer Prevention Research (in press)

Shepherd SO, Strauss JA, Wang Q, Dube JJ, Goodpaster BH, Mashek DG, Chow LS. Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure. Journal of Physiology (in press)

Franklin MP, Sathyanarayan A, Mashek DG. Acyl-CoA Thioesterase 1 (ACOT1) regulates PPARα to couple fatty acid flux with oxidative capacity during fasting. Diabetes 2017;66(8):2112-2123

Chow LS, Mashek DG, Wang Q, Shepherd SO, Goodpaster BH, Dube JJ. Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type specific IMCL accumulation. Journal of Applied Physiology 2017;123(1):71-78.

Sathyanarayan S, Mashek MT, Mashek DG. ATGL promotes autophagy/lipophagy via SIRT1 to control hepatic lipid droplet catabolism. Cell Reports 2017;19(1):1-9.

Kamarajugadda S, Becker JR, Hanse EA, Mashek DG, Mashek MT, Hendrickson AM, Mullany LK, Albrecht JH. Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation. Oncotarget 2016;7(30):47674-47686.

Zhang W, Bu SY, Mashek MT, O-Sullivan I, Sabai Z, Khan SA, Ilkayeva O, Newgard CB, Mashek DG*, Unterman TG*. Integrated regulation of hepatic lipid and glucose metabolism by adipose triacylglycerol lipase and FoxO proteins. Cell Reports 2016;5(2):349-359.  *Co-corresponding authors

Bowman TA, O’Keeffe KR, D’Aquila T, Yan QW, Griffin JD, Killion EA, Mashek DG, Buhman KK, Greenberg AS.  Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption. Molecular Metabolism 2016;5(3):210-220.

Khan SA, Wollaston-Hayden EE, Markowski TW, Higgins L, Mashek DG. Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis. Journal of Lipid Research 2015;56(12):2260-2272.

Khan SA, Sathyanarayan S, Mashek MT, Ong KT, Wollaston-Hayden EE, Mashek DG. ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling. Diabetes 2015;64:418–426.

 

 

Reviews:

Schulze RJ, Sathyanarayan A, Mashek DG.  Breaking fat: the regulation and mechanisms of lipophagy. BBA - Molecular and Cell Biology of Lipids (in press)

Mulukutla BC, Yongky A, Le T, Mashek DG, Hu WS. Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing. Trends in Biotechnology 2016;16:S0167-7799.

Mashek DG, Khan SA, Sathyanarayan A, Ploeger JM, Franklin MP. Hepatic lipid droplet biology: Getting to the root of fatty liver. Hepatology 2015;62(3):964-967.

Mashek DG, Wu C.  MUFAs. Advances in Nutrition 2015;6(3):276-277.

Mashek DG. Hepatic fatty acid trafficking: multiple forks in the road. Advances in Nutrition 2013;4(6):697-710.

Greenberg AS, Coleman RA, Kraemer FB, McManaman JL, Obin MI, Puri V, Yan QW, Miyoshi H, Mashek DG. The role of lipid droplets in metabolic disease in rodents and humans. Journal of Clinical Investigation 2011;121(6):2102-2110.

Coleman RA, Mashek DG. Mammalian triacylglycerol metabolism: synthesis, lipolysis and signaling. Chemical Reviews 2011;111(10):6359-6386.

A complete list of publications is available via PubMed